Thats one of the things I hate about default chat channels. Since this thread seems to be headed in the perfect direction for a rant......
<rant>
I really hate how the default chat channel is Guild (with default settings). I don't always play EQ / the same character on the same computer. Default goes to Guild. I haven't had any MacroQuest MT's to my guild, but that scares the crap out of me.
The best channel to be in is Say. Most people don't have say going to a seperate window. Plus, whatever you say in "say", only limited people see. Granted many will see it in the bazaar, but you can get in big trouble if your default chan is OOC.
Anything default channels besides say (even group) are asking for trouble. Not just with MacroQuest but with any communication in general. Whether your talking shit about a guildie, accidentally saying "target npc", etc the damage will likely be minimized if you simply /say it.
After all, talking to guild takes a "/gu", talking to group takes a "/g", and talking to a chat channel takes /1. Finding a new guild because you got kicked out

after typing "/macro genbot" three times

takes a whole LOT more keystrokes than that.
Just a humble suggestion =)
</rant>
Also, for the VERY paranoid people: If you use hot buttons for all of your macros, you will NEVER have mistells. Even if you mistype stuff, hot buttons will not chat without a chat channel specified (98% sure).